Dr. Daniel Labow

Surgical Oncologist at Mount Sinai Health System

Dr. Daniel Labow is a proponent of HIPEC with cytoreductive surgery for malignant peritoneal mesothelioma. He also is a lead surgeon at Mount Sinai Health System’s cancer center. He has helped hundreds of patients through surgery.

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Peritoneal Mesothelioma

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Mount Sinai Health System

1190 One Gustave L. Levy Place, New York, NY 10029

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More About Mesothelioma Specialist Dr. Daniel Labow

Dr. Labow joined Mount Sinai Health System in 2004 and three years later began the peritoneal surface malignancies program. He sees patients at the hospital’s cancer affiliate, the Tisch Cancer Institute.

Since then, he has performed more than 750 procedures involving HIPEC. This is heated intraperitoneal chemotherapy. It specifically addresses small microscopic tumors in the abdominal cavity. Many peritoneal mesothelioma patients live much longer than expected thanks to HIPEC.

A small percentage of those procedures involve peritoneal mesothelioma, but it’s enough to classify Dr. Labow as a specialist.

“In the last six months, I’ve probably seen seven or eight mesothelioma cases,” he said. “The awareness of HIPEC has become more prevalent. … I feel like the curve is increasing at a faster rate.”

In addition to being a surgical oncologist, Dr. Labow is:

  • Executive Vice-Chair of the Department of Surgery
  • Vice Chair of Quality for the Department of Surgery
  • Program Director of Mount Sinai Health System’s surgical oncology fellowship

He’s also a professor in surgery at the Icahn School of Medicine, affiliated with Mount Sinai Health System.

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Medical Degrees and Residencies

    • Medical Degree from Brown-Dartmouth Medical Program, 1995
    • Residency in general surgery at the University of Chicago Hospitals
    • Fellowship in surgery oncology at Memorial Sloan Kettering Cancer Center
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Certifications and Memberships

    • Board-certified in general surgery
    • Membership in the American College of Surgeons, American Hepatopancreaticobiliary Association and Society of Surgical Oncology
    • Co-Chair of the Gastrointestinal Disease Focus Group at Mount Sinai Health System

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Dr. Labow is one of the leading surgeons for peritoneal mesothelioma. He’s a strong communicator and prioritizes patient quality of life. He also leaves open the possibility of surgery or other therapies with neoadjuvant treatment. Dr. Labow works at one of the top cancer centers in the northeast.

Why Choose Dr. Labow?

  • Proponent of HIPEC with debulking surgery
  • Belief in immunotherapy for specific cases
  • Performed nearly 1,000 surgeries in career


Family History in Medical Care

Dr. Labow’s father was a physician, his mother was a biochemist and his brother is a pediatric surgeon. The medical profession runs in the family, an inspiration for his life’s work.

“It definitely started me on the science and medical pathway,” he said, noting he enjoys having long-term relationships with patients.

“I really like longitudinal patient care, seeing patients over time. Having a long-term relationship with patients you realize the privilege of having a relationship with patients during this vulnerable time.

“That is always the most rewarding thing.”

Dr. Labow remembers multiple stories of patients sending him Christmas messages or other notes years after surgery and treatment ended. They owe their lives to his expert surgical hand.

“Some of the notes are patients saying I bought them two or three more years to see the birth of their grandchild,” he said.

Deciding on whether to perform mesothelioma surgery is one of the toughest parts of treatment. If the tumors spread too much, any surgery can be too risky without a long-term survival improvement.

“As a physician, we need to listen to the patient,” Dr. Labow said. “We can have the same conversation with two different patients, say the same words, and they’ll want two different things.”

Improved Mortality Rates for HIPEC Surgery

The mortality rates for HIPEC surgery were once worrisome. Now they’re below 1%, which is less than pancreatic surgery and esophageal surgery.

“We’ve got the safety of the operation down pretty well,” he said. “Our patient selection is better.”

The process is also much better. He removes the omentum and likely is aggressive in resecting the peritoneal lining. This lining covers the abdominal cavity and is where peritoneal mesothelioma forms.

Other organs he possibly removes are the spleen and part of the small bowel. Ablation can help with eliminating tumors without hurting an organ.

Dr. Labow uses laparoscopy to uncover the scope of the cancer. It provides him a visual idea of the tumors within the abdominal cavity.

“If I send the patient for neoadjuvant therapy, I have a visual in my head for if they undergo therapy for 3-6 months,” he said.

Support for Immunotherapy as an Option

Dr. Labow is one of many surgeons who sees value in immunotherapy for mesothelioma. The treatment isn’t yet approved for peritoneal mesothelioma, although it is approved by the U.S. Food and Drug Administration for pleural mesothelioma.

“I think the dual immunotherapy protocol with nivolumab and ipilimumab is one of the best innovations,” he said. “It used to be that all you had was HIPEC. We’d do it and there wasn’t another avenue. I’m not a believer in a single bullet for cancer.

“Having an immunotherapy regimen in our back pocket will probably make more patients eligible for the HIPEC surgery to clean up the residual disease.”

Dr. Labow sees patients from anywhere in the United States. People in the northeast have quick access to Mount Sinai’s cancer center, but those in other regions can get financial help traveling to him. If you want to meet Dr. Labow personally, we can help. Please send us your contact and diagnosis information through our free Doctor Match form.

Sources & Author

    1. Daniel M Labow, MD. Mount Sinai. Retrieved from: https://www.mountsinai.org/profiles/daniel-m-labow. Accessed: 09/14/2021.
Devin Golden

About the Writer, Devin Golden

Devin Golden is a content writer for Mesothelioma Guide. He produces mesothelioma-related content on various mediums, including the Mesothelioma Guide website and social media channels. Devin's objective is to translate complex information regarding mesothelioma into informative, easily absorbable content to help patients and their loved ones.