On May 24, 2019, for the first time in 15 years, the United States Food and Drug Administration approved a treatment for mesothelioma.

Nearly two years later, the NovoTTF-100L System is accessible in more than 70 hospitals spanning 31 states. The therapy, which was rebranded in the past year to “Optune Lua”, achieved a successful year growing its imprint and helping people with pleural mesothelioma.

The NovoTTF-100L is a tumor treating fields device, which sends electrical currents into the body. These electrical waves can disrupt and kill cancer cells. In the first year since FDA approval, Novocure’s device has checked off quite a few accomplishments. Many more are still to come.

If you have pleural mesothelioma and want to learn more about the NovoTTF-100L System (Optune Lua), we can answer your questions. We also can connect you to a hospital that offers the treatment. Email our patient advocate and registered nurse, Karen Ritter, at karen@mesotheliomaguide.com to see if you’re a candidate for this therapy.


NovoTTF-100L Makes History

Novocure, the manufacturer and creator of the NovoTTF-100L System, spent years conceptualizing and researching the benefits of tumor treating fields. The company put its experimental treatment through the FDA’s rigorous clinical testing process.

Last May, that hard work paid off. The FDA approved the NovoTTF-100L System for “humanitarian use device” distinction. It could be used:

  • For “locally advanced or metastatic malignant pleural mesothelioma,” as described in Novocure’s press release
  • Only in combination with chemotherapy
  • Only when surgery isn’t an option

The NovoTTF-100L device delivers low-intensity electrical currents into the disease location. Patients wear the therapy on their body for most of the day and night, and they hardly notice its effects.

For pleural mesothelioma, the therapy sends these fields into the pleura, which is the thin lining between your chest wall and lung cavity where pleural mesothelioma forms. Novocure researchers believe that mesothelioma cells are sensitive to these currents.


NovoTTF-100L Gets a New Name: Optune Lua

In March, the NovoTTF-100L System received a name change. It was rebranded “Optune Lua” to promote “the prospect of hope and optimized care,” according to Novocure chief commercial officer Pritesh Shah.

He said the name change is easy for patients to remember and can help them, along with caregivers and others, “ask for the treatment by name.”

Optune Lua has the hopeful survival data to go with its assuring name. The FDA approval last May came on the heels of the phase 2, STELLAR clinical trial.

The median overall survival for 80 participants using the NovoTTF-100L plus chemotherapy was 18.2 months. Around 62% survived for at least one year, and the disease control rate was 97%. Approximately 40% showed a partial response, meaning their cancer shrunk slightly in size.


Which Hospitals Offer the Treatment

In September 2019, West Cancer Clinic (Germantown, Tennessee) became the first hospital to offer the NovoTTF-100L device. It also became the first hospital to prescribe the therapy to a mesothelioma patient.

Since then, hospitals in each part of the United States have welcomed Optune Lua for pleural mesothelioma. The full list of the medical institutions that offer Optune Lua is below:

  • Abbott Northwestern Hospital (Minneapolis, Minnesota)
  • Agnesian Cancer Center (Fond du Lac, Wisconsin)
  • Allegheny Health Network and Allegheny General Hospital (Pittsburgh, Pennsylvania)
  • Atlantic Health System (Morristown, New Jersey)
  • Banner MD Anderson Cancer Center (Gilbert, Arizona)
  • Baylor Charles A. Sammons Cancer Center (Dallas, Texas)
  • Baylor St Luke’s Medical Center (Houston, Texas)
  • Beaumont Health System (Michigan) — Royal Oaks; Troy (Sterling Heights); Dearborn
  • Bothwell Regional Health Center (Sedalia, Missouri)
  • Brigham and Women’s Hospital (Boston)
  • Cancer Center of Hawaii (Honolulu)
  • Charleston Oncology (South Carolina)
  • Cleveland Clinic (Cleveland, Ohio)
  • Clinical Research Center (Fairway, Kansas)
  • Coastal Cancer Center (Myrtle Beach, South Carolina)
  • Comprehensive Cancer Centers (Henderson, Nevada)
  • Ellis Fischel Cancer Center (Columbia, Missouri)
  • Epic Care Cyberknife (Walnut Creek, California)
  • Erlanger Cancer Institute (Chattanooga, Tennesse)
  • Fitzgibbon Cancer Center (Marshall, Missouri)
  • Frye Regional Medical Center (Hickory, North Carolina)
  • George W. Rea Cancer Treatment (Kirksville, Missouri)
  • Goldschmidt Cancer Center (Jefferson City, Missouri)
  • Goshen Health (Goshen, Indiana)
  • HaysMed Dreiling Schmidt Cancer Institute (Hays, Kansas)
  • Hematology Oncology of The North Shore (Skokie, Illinois)
  • Hematology Oncology Life Center (Alexandria, Louisiana)
  • Iyengar Hematology Oncology Medical Center (Bayonne, New Jersey)
  • James E. Cary Cancer Center (Hannibal, Missouri)
  • Lake Regional Cancer Center (Osage Beach, Missouri)
  • Loyola University Medical Center (Maywood, Illinois)
  • Massachusetts General Hospital (Boston)
  • McFarland Clinic (Ames, Iowa)
  • Miami (Florida) Cancer Institute
  • Missouri Cancer Associates, LLC. (Columbia, Missouri)
  • Moffitt Cancer Center (Tampa, Florida)
  • New York Proton Center (New York)
  • Novant Health Medical Center (Winston-Salem, North Carolina; Huntersville, North Carolina; Charlotte, North Carolina; Kernersville, North Carolina)
  • Ochsner Medical Center (New Orleans, Louisiana; Baton Rouge, Louisiana)
  • Ohio State University (Columbus)
  • Oregon Health and Science University (Portland)
  • Piedmont Healthcare (Atlanta)
  • Prisma Health (Greenville, South Carolina)
  • Richard and Annette Bloch Cancer Center Pavillion (Westwood, Kansas; Kansas City, Kansas)
  • Rochester Regional Health (New York)
  • Ronald Reagan UCLA Medical Center (Los Angeles)
  • Sanford Health (Fargo, North Dakota)
  • Seattle Cancer Center (Renton, Washington)
  • Spartanburg Regional Medical Center (Spartanburg, South Carolina)
  • St. Elizabeth Healthcare (Edgewood, Kentucky)
  • St. Mary’s Hospital and Regional Medical Center (Grand Junction, Colorado; Wheat Ridge, Colorado)
  • St. Jude Crosson Cancer Institute (Fullerton, California)
  • Sutter Health (Sacramento, California)
  • Swedish Cancer Institute (Seattle, Washington)
  • Tri-Cities Cancer Center (Kennewick, Washington)
  • University Health Care System (Augusta, Georgia)
  • University of Kansas Cancer Center (Westwood, Kansas; Overland Park, Kansas; Kansas City, Missouri; Summit, Missouri)
  • University of Kansas Health System (Topeka)
  • University of Maryland Medical Center (Baltimore)
  • University of Miami (Florida) Health System
  • Virginia Cancer Institute (Henrico)
  • Virginia Oncology Associates (Hampton; Williamsburg)
  • West Cancer Clinic (Germantown, Tennessee)
  • William R. Bliss Cancer Center (Ames, Iowa)

If you’d like to look based on geography, the 31 states (cities in parenthesis) with hospitals offering Optune Lua are:

  • Arizona (Gilbert)
  • California (Walnut Creek; Los Angeles; Sacramento; Fullerton)
  • Colorado (Grand Junction; Wheat Ridge)
  • Florida (Miami; Tampa)
  • Georgia (Augusta; Atlanta)
  • Hawaii (Honolulu)
  • Illinois (Maywood; Skokie)
  • Indiana (Goshen)
  • Iowa (Ames)
  • Kansas (Fairway; Hays; Kansas City; Overland Park; Topeka; Westwood)
  • Kentucky (Edgewood)
  • Louisiana (Alexandria; Baton Rouge; New Orleans)
  • Maryland (Baltimore)
  • Massachusetts (Boston)
  • Michigan (Dearborn; Royal Oak; Sterling Heights)
  • Minnesota (Minneapolis)
  • Missouri (Summit; Kansas City; Sedalia; Columbia; Marshall; Kirksville; Jefferson City; Hannibal; Osage Beach)
  • Nevada (Henderson)
  • New Jersey (Bayonne; Morristown)
  • New York (Rochester; New York City)
  • North Carolina (Hickory; Winston-Salem; Huntersville; Charlotte; Kernersville)
  • North Dakota (Fargo)
  • Ohio (Cleveland; Columbus)
  • Oregon (Portland)
  • Pennsylvania (Pittsburgh)
  • South Carolina (Charleston; Greenville; Myrtle Beach; Spartanburg)
  • Tennessee (Chattanooga; Germantown)
  • Texas (Dallas; Houston)
  • Virginia (Hampton; Henrico; Williamsburg)
  • Washington (Kennewick; Renton; Seattle)
  • Wisconsin (Fond du Lac)
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    Sources & Author

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About the Writer, Devin Golden

Devin Golden is the content writer for Mesothelioma Guide. He produces mesothelioma-related content on various mediums, including the Mesothelioma Guide website and social media channels. Devin's objective is to translate complex information regarding mesothelioma into informative, easily absorbable content to help patients and their loved ones.