DREAM Clinical Trial Produces Encouraging Results
A clinical trial hosted in Australia may have victorious results in treating pleural mesothelioma. However, researchers agree that more testing needs to occur.
During the study, 54 patients were recruited. They were treated with first-line chemotherapy (cisplatin and pemetrexed) and the immunotherapy drug durvalumab.
For up to six treatment cycles, participants received chemotherapy and durvalumab. Patients continued receiving durvalumab on its own until they completed 12 months of treatment or their mesothelioma progressed.
Later this year researchers will release their finalized report.
Using Immunotherapy to Treat Mesothelioma
There is one treatment that is changing the way that mesothelioma patients combat their disease. That treatment is immunotherapy.
Currently, this treatment option is still considered an experimental approach to treating mesothelioma. The only way a patient can experience it is by enrolling in a clinical trial or on a compassionate care basis.
Immunotherapy cancer drugs are designed to use a patient’s immune system to help combat their disease. It is a form of targeted therapy that avoids a patient’s healthy cells and zones in on attacking only their cancerous mesothelioma cells.
Learn more about how immunotherapy works in our short video:
Several mesothelioma patients, especially late stage, have had positive treatment experiences. Immunotherapy has fewer side effects, and it has exhibited signs of slowing down and managing a patient’s disease.
U.S. Clinical Trial Results TBA
In the United States, a clinical trial similar to DREAM is presently active in 20 different locations. 55 participants are currently enrolled. The study started in 2017 and anticipates to have results by 2020.
Primary investigator of the trial is Dr. Patrick Forde. He is a well-respected name in the mesothelioma community. Dr. Forde is active in both researching and treating patients at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center in Maryland.
Immunotherapy for Mesothelioma at Johns Hopkins
Johns Hopkins is home to the Bloomberg~Kimmel Institute for Cancer Immunotherapy (BKI). The institute was established in 2016. However, medical experts at Johns Hopkins have been actively involved in pioneering immunotherapy drugs for almost 30 years.